Rabbit anti‑Human CCKBR / Cckb Polyclonal RW-A1282-50

Antibody: CCKBR / Cckb Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody, Application: IHC, IHC-P, Reactivity: Human, Format: Unconjugated, Unmodified, Descriptio: Cholecystokinin B receptor (CCKBR) is found in the central nervous system where it modulates anxiety, analgesia, arousal, and neuroleptic activity. CCKBR mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.

References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804, Targe: Human CCKBR / Cckb, Synonym: CCKBR | CCKB | Cholecystokinin-2 receptor | CCK-BR | CCK2 receptor | CCK2-R | CCKB-R | Cholecystokinin-B | GASR | CCK-B | CCK-B receptor | CCK2R | Cckb receptor | CCKRB | Cholecystokinin B receptor | Gastrin receptor, Hos: Rabbit, Reactivit: Human (tested or 100% immunogen sequence identity), Clonalit: Polyclonal, Conjugation: Unconjugated, Purificatio: Immunoaffinity purified, Modification: Unmodified, Immunoge: Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human CCKBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Monkey (83%)., Epitop: Cytoplasmic Domain, Specificit: Human CCKBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins., Application: IHC
IHC - Paraffin (3 µg/ml), Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more: None, Presentatio: PBS, 0.1% Sodium Azide, Storag: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles., Restriction: For research use only. Intended for use by laboratory professionals., Guarante: This antibody carries the RW 100% Guarantee., About CCKBR / Cck: Uniprot: P32239 NCBI: NM_176875 NP_795344.1

Cat: RW-52-65942-113