Rabbit anti‑Mouse CD3E IgG Polyclonal RW-C389467-100

Antibody: CD3E Rabbit anti-Mouse Polyclonal (Azide-free, BSA-free) Antibody, Application: WB, IP, Flo, Reactivity: Mouse, Human, Orangutan, Monkey, Rat, Bovine, Hamster, Horse, Pig, Rabbit, Sheep, Format: Unconjugated, Azide-free, BSA-free, Other formats: Unmodified, Descriptio: CD3E antibody RW-C389467 is an unconjugated rabbit polyclonal antibody to CD3E from mouse. It is reactive with human, mouse, rat and other species. Validated for Flow, IP and WB., Targe: Mouse CD3E, Synonym: CD3E | CD3e antigen | CD3-epsilon | T-cell receptor epsilon chain | TCRE | T-cell receptors epsilon chain | T3E | CD3 Epsilon | CD3, Hos: Rabbit, Reactivit: Mouse, Human, Orangutan, Monkey, Rat, Bovine, Hamster, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity), Clonalit: IgG Polyclonal, Conjugation: Unconjugated, Purificatio: Protein A purified, Modification: Azide-free, BSA-free. Also available Unmodified., Immunoge: Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%); Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%)., Specificit: Mouse CD3e., Application: Western blot (0.5 - 1 µg/ml)
Immunoprecipitation
Flow Cytometry (0.5 - 1 µg/10E6 cells), Usag: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms., Presentatio: 1X PBS, Storag: Store at 2°C to 8°C., Restriction: For research use only. Intended for use by laboratory professionals., Guarante: This antibody carries the RW 100% Guarantee., About CD3: NCBI: NM_000733 NP_000724.1

Cat: RW-52-76488-85